IFN Alpha Monoclonal antibody proteintech 66162-1-Ig

$449.00
In stock
SKU
66162-1-Ig

 

IFL, IFN, IFN ALPHA, IFN alpha 1/13, IFNA@, IFNA1, IFNA13, IFN-alpha, LeIF D

Host / Isotype: Mouse / IgG2a Class: Monoclonal
Reactivity: human Immunogen: CatNo: Ag12533 Product name: Recombinant human IFNA1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 24-189 aa of BC074928 Sequence: CDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFGFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLEACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTNLQERLRRKE Predict reactive species
 Applications: WB, ELISA Observed Molecular Weight: 189 aa, 22 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC074928
Conjugate: Unconjugated Gene Symbol: IFN alpha1
Tested Applications: Positive WB detected in Gene ID (NCBI): 3439
Application: Western Blot (WB) RRID: AB_2881558
Dilution: WB : 1:500-1:1000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Mouse / IgG2a Background Information: IFNA1 (IF-alpha) is a member of the Type I IFN (1) family best known for their antiviral activity. It is a key cytokine regulating the activity of B cells, T-helper cells (Th cells), cDCs and natural killer cells (NK cells). IFNA1 induces B cell maturation into plasma cells and immunoglobulin production. IFNA1 plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). IFNA1 was the first cytokine to show clinical benefit in the treatment of certain types of cancer, including melanoma, chronic myelogenous leukemia, and renal cancer.

 

 

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