GRP75 Monoclonal antibody proteintech 67563-1-Ig

$449.00
In stock
SKU
67563-1-Ig

 

HSPA9, 2B12F2, 75 kDa glucose-regulated protein, CSA, GRP-75

Host / Isotype: Mouse / IgG2a Class: Monoclonal
Reactivity: human, mouse, rat Immunogen: CatNo: Ag7125 Product name: Recombinant human GRP75 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 331-679 aa of BC000478 Sequence: YLTMDSSGPKHLNMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKEDQKEEKQ Predict reactive species
 Applications: WB, IHC, ELISA Observed Molecular Weight: 74 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC000478
Conjugate: Unconjugated Gene Symbol: GRP75
Tested Applications: Positive WB detected in Gene ID (NCBI): 3313
Application: Western Blot (WB) RRID: AB_2882777
Dilution: WB : 1:2000-1:10000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Mouse / IgG2a Background Information: GRP75 (also known as mortalin, HSPA9 or mt-Hsp70) is a constitutively expressed member of the HSPA (HSP70) family of heat-shock proteins. It is located in the mitochondrial matrix and anti-GRP75 is commonly used as the marker for mitochondria. It has been reported that GRP75 is enriched in cancer cells and contributes to carcinogenesis. In addition, decreased expression level of GRP75 has been found in neurodegenerative disorders like Parkinson's disease. (PMID: 21640711, 229209024)

 

 

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