C5 Monoclonal antibody proteintech 66634-1-Ig
$449.00
In stock
SKU
66634-1-Ig
C5, C5a, C5, C5b, 2G8C9, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, C5a
| Host / Isotype: Mouse / IgG2a | Class: Monoclonal |
| Reactivity: human | Immunogen: CatNo: Ag17882 Product name: Recombinant human C5, C5a protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1418-1676 aa of BC113740 Sequence: GSSHAVMDISLPTGISANEEDLKALVEGVDQLFTDYQIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMFYSTSNIKIQKVCEGAACKCVEADCGQMQEELDLTISAETRKQTACKPEIAYAYKVSITSITVENVFVKYKATLLDIYKTGEAVAEKDSEITFIKKVTCTNAELVKGRQYLIMGKEALQIKYNFSFRYIYPLDSLTWIEYWPRDTTCSSCQAFLANLDEFAEDIFLNGC Predict reactive species |
| Applications: WB, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 1676 aa, 188 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC113740 |
| Conjugate: Unconjugated | Gene Symbol: C5 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 727 |
| Application: Western Blot (WB) | RRID: AB_2881993 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG2a | Background Information: The complement system is an important effector that bridges the innate and adaptive immune systems. The fifth component of complement, C5, is part of the complement cascade and plays an important role in inflammation and cell killing. It consists of disulfide-linked alpha and beta polypeptide chains but can be cleaved into two active peptides (C5a and C5b) by C5 convertases. Mutations and defects in C5 are associated with severe recurrent infections. (PMID: 20010915; PMID: 8011297; PMID: 6554279) |
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