BAD Polyclonal antibody proteintech 10435-1-AP

$449.00
In stock
SKU
10435-1-AP

 

BBC2, BBC6, Bcl2-associated agonist of cell death, Bcl-2-binding component 6, BCL2L8

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse And More (4) Immunogen: CatNo: Ag0688 Product name: Recombinant human BAD protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 14-168 aa of BC001901 Sequence: DSSSAERGLGPSPAGDGPSGSGKHHRQAPGLLWDASHQQEQPTSSSHHGGAGAVEIRSRHSSYPAGTEDDEGMGEEPSPFRGRSRSAPPNLWAAQRYGRELRRMSDEFVDSFKKGLPRPKSAGTATQMRQSSSWTRVFQSWWDRNLGRGSSAPSQ Predict reactive species
 Applications: WB, IHC, FC (Intra), ELISA Observed Molecular Weight: 18 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC001901
Conjugate: Unconjugated Gene Symbol: BAD
Tested Applications: Positive WB detected in Gene ID (NCBI): 572
Application: Western Blot (WB) RRID: AB_2061994
Dilution: WB : 1:500-1:3000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: BAD, also named as BBC6 and BCL2L8, promotes cell death. It is successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. BAD can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. It appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

 

 

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