Anti-Human CD3 (OKT3) proteintech 65133-1-Ig
$42.00
In stock
SKU
65133-1-Ig
CD3E, CD3 epsilon, T-cell surface antigen T3/Leu-4 epsilon chain, T3E, OKT3
| Host / Isotype: Mouse / IgG2a, kappa | Class: Monoclonal |
| Reactivity: human | Immunogen: Human T cells Predict reactive species |
| Applications: IHC, FC, Cell treatment | Observed Molecular Weight: 207 aa, 23 kDa |
| Formulation: PBS, Azide | GenBank Accession Number: CD3 |
| Conjugate: Unconjugated | Gene Symbol: 916 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): ENSG00000198851 |
| Application: Flow Cytometry (FC) | RRID: AB_2918421 |
| Dilution: FC : 0.2 ug per 10^6 cells in 100 μl suspension | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG2a, kappa | Background Information: CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657). |
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