RND3 Monoclonal antibody proteintech 66228-1-Ig
$449.00
In stock
SKU
66228-1-Ig
ARHE, memB, Protein MemB, Rho family GTPase 3, Rho8, RhoE, RND3
| Host / Isotype: Mouse / IgG2b | Class: Monoclonal |
| Reactivity: human, pig | Immunogen: CatNo: Ag18839 Product name: Recombinant human RND3 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-244 aa of BC012513 Sequence: MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKSCTVM Predict reactive species |
| Applications: WB, IF, ELISA | Observed Molecular Weight: 244 aa, 27 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC012513 |
| Conjugate: Unconjugated | Gene Symbol: RND3 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 390 |
| Application: Western Blot (WB) | RRID: AB_2881619 |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Unconjugated |
| Tested Reactivity: human, pig | Form: Liquid |
| Host / Isotype: Mouse / IgG2b | Background Information: Rnd3, also known as RhoE, belongs to the Rnd subclass of the Rho family of small guanosine triphosphate (GTP)-binding proteins. Rnd proteins are unique due to their inability to switch from a GTP-bound to GDP-bound conformation. The basic role of?Rnd3?is to report as an endogenous antagonist of RhoA signaling-mediated actin cytoskeleton dynamics, which specifically contributes to cell migration and neuron polarity. Rnd3?also plays a critical role in arresting cell cycle distribution, inhibiting cell growth, and inducing apoptosis and differentiation. |
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