PSMD2 Monoclonal antibody proteintech 67770-1-Ig
$449.00
In stock
SKU
67770-1-Ig
TRAP2, S2, Rpn1, P97, 26S proteasome non-ATPase regulatory subunit 2
| Host / Isotype: Mouse / IgG2a | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 |
| Applications: WB, ELISA | Observed Molecular Weight: 100 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: PSMD2 |
| Conjugate: Unconjugated | Gene Symbol: 5708 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_2918536 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:20000-1:100000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purification |
| Host / Isotype: Monoclonal | Background Information: Tumor necrosis factor type 1 receptor-associated protein 2 (TRAP2), encoded by PSMD2 gene, is a non-ATPase regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. TRAP2 may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. |