PSMD2 Monoclonal antibody proteintech 67770-1-Ig

$449.00
In stock
SKU
67770-1-Ig

 

TRAP2, S2, Rpn1, P97, 26S proteasome non-ATPase regulatory subunit 2

Host / Isotype: Mouse / IgG2a Class: Antibody
Reactivity: human, mouse, rat Immunogen: proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
 Applications: WB, ELISA Observed Molecular Weight: 100 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: PSMD2
Conjugate: Unconjugated Gene Symbol: 5708
Tested Applications: Positive WB detected in Gene ID (NCBI): AB_2918536
Application: Western Blot (WB) RRID: Unconjugated
Dilution: WB : 1:20000-1:100000 Conjugate: Liquid
Tested Reactivity: Human, Mouse, Rat Form: Protein A purification
Host / Isotype: Monoclonal Background Information: Tumor necrosis factor type 1 receptor-associated protein 2 (TRAP2), encoded by PSMD2 gene, is a non-ATPase regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. TRAP2 may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor.

 

 

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