CD200 Monoclonal antibody proteintech 66282-1-Ig

$449.00
In stock
SKU
66282-1-Ig

 

CD200 molecule, MOX1, MOX2, MRC, OX 2

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: human Immunogen: CatNo: Ag5045 Product name: Recombinant human CD200 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-269 aa of BC022522 Sequence: MERLVIRMPFCHLSTYSLVWVMAAVVLCTAQVQVVTQDEREQLYTPASLKCSLQNAQEALIVTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLGLQNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPIVSLHYKFSEDHLNITCSATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKEVICQVLHLGTVTDFKQTVNKGYWFSVPLLLSIVSLVILLVLISILLYWKRHRNQDREP Predict reactive species
 Applications: WB, IHC, IF, ELISA Observed Molecular Weight: 269 aa, 30 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC022522
Conjugate: Unconjugated Gene Symbol: CD200
Tested Applications: Positive WB detected in Gene ID (NCBI): 4345
Application: Western Blot (WB) RRID: AB_2881665
Dilution: WB : 1:1000-1:4000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Mouse / IgG1 Background Information: CD200, also known as OX2, is a type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily (PMID: 3032785). It contains two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. CD200 is expressed on a variety of cell types, including thymocytes, B lymphocytes, a subset of T lymphocytes, follicular dendritic cells, neurons, and endothelial cells (PMID: 3032785; 10981966). CD200 binds to its receptor, CD200R, which is primarily expressed by myeloid and T cell lineage (PMID: 15187158). The CD200-CD200R interaction plays a role in immunosuppression and suppression of anti-tumor immune responses (PMID: 22020332).

 

 

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