Anti-Mouse CD11b (M1/70) proteintech 65055-1-Ig
$68.00
In stock
SKU
65055-1-Ig
CR3, CR3A, integrin alpha M, Itgam, Ly 40
| Host / Isotype: Rat / IgG2b, kappa | Class: Monoclonal |
| Reactivity: human, mouse, rabbit, monkey, guinea pig, non-human primates | Immunogen: C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes Predict reactive species |
| Applications: IF, FC | Observed Molecular Weight: 127 kDa |
| Formulation: PBS, Azide | GenBank Accession Number: CD11b |
| Conjugate: Unconjugated | Gene Symbol: 16409 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): AB_2918363 |
| Application: Flow Cytometry (FC) | RRID: Unconjugated |
| Dilution: FC : 0.2 ug per 10^6 cells in 100 μl suspension | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rabbit, Monkey, Guinea Pig, Non-Human Primates | Form: Protein G purification |
| Host / Isotype: Rat / IgG2b, kappa | Background Information: Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828). |
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