IMPDH2 Polyclonal antibody proteintech 12948-1-AP
$449.00
In stock
SKU
12948-1-AP
EC:1.1.1.205, IMP dehydrogenase II, IMPD 2, IMPD2, IMPDH 2
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse, Rat And More (1) | Immunogen: CatNo: Ag3632 Product name: Recombinant human IMPDH2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-350 aa of BC012840 Sequence: MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKV Predict reactive species |
| Applications: WB, IHC, IF/ICC, IP, RIP, ELISA | Observed Molecular Weight: 514 aa, 56 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC012840 |
| Conjugate: Unconjugated | Gene Symbol: IMPDH2 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 3615 |
| Application: Western Blot (WB) | RRID: AB_2127351 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: IMPDH2, also named as IMPD2, belongs to the IMPDH/GMPR family. It is a rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors. IMPDH2 is a key enzyme in the purine nucleotide biosynthetic pathway and constitutes a pivotal biological target for immunosuppressant and antiviral drugs. (PMID:21181270) IMPDH2 is highly enriched in RR(filamentous rods and rings). This antibody may have cross-reaction with IMPDH1 due to the high homology. |
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