Angiopoietin 1 Monoclonal antibody proteintech 68618-1-Ig

$449.00
In stock
SKU
68618-1-Ig

 

ANGPT1, ANG-1, ANG1, ANG 1, AGPT

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: human, mouse Immunogen: CatNo: Ag18829 Product name: Recombinant human ANGPT1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 161-293 aa of BC152411 Sequence: IQLLENSLSTYKLEKQLLQQTNEILKIHEKNSLLEHKILEMEGKHKEELDTLKEEKENLQGLVTRQTYIIQELEKQLNRATTNNSVLQKQQLELMDTVHNLVNLCTKEGVLLKGGKREEEKPFRDCADVYQAG Predict reactive species
 Applications: WB, IF/ICC, ELISA Observed Molecular Weight: 498 aa, 58 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC152411
Conjugate: Unconjugated Gene Symbol: Angiopoietin 1
Tested Applications: Positive WB detected in Gene ID (NCBI): 284
Application: Western Blot (WB) RRID: AB_3085311
Dilution: WB : 1:2000-1:10000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse Form: Liquid
Host / Isotype: Mouse / IgG1 Background Information: Angiopoietin 1 is a 70-kDa secreted glycoprotein generated from vascular mural cells, pericytes, and certain other cells. Angiopoietin 1 participates in vascular differentiation through angiogenesis, which is the process of the growth and remodelling of existing vessels. Angiopoietin 1 is also involved in the maintenance and turnover of blood vessels in mature animals. Angiopoietin 1 binds to and activates the TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation, playing an important role in the regulation of angiogenesis. Overexpression of Angiopoietin 1 has been proven to occur in malignant glioblastoma, neuroblastoma, non-small cell lung cancer, and other tumors.

 

 

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