VDAC1/2 Polyclonal antibody proteintech 10866-1-AP
$189.00
In stock
SKU
10866-1-AP
Porin, VDAC1, VDAC1/Porin, hVDAC1, Plasmalemmal porin
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse, Rat And More (5) | Immunogen: CatNo: Ag1144 Product name: Recombinant human Porin protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-283 aa of BC008482 Sequence: MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA Predict reactive species |
| Applications: WB, IHC, IF-P, IF-Fro, FC (Intra), CoIP, ELISA | Observed Molecular Weight: 31 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC008482 |
| Conjugate: Unconjugated | Gene Symbol: Porin |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 7416 |
| Application: Western Blot (WB) | RRID: AB_2257153 |
| Dilution: WB : 1:500-1:3000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: VDAC1, also named as VDAC, porin 31HM, porin 31HL and plasmalemmal porin, belongs to the eukaryotic mitochondrial porin family. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV, to form a channel through the mitochondrial outer membrane and also the plasma membrane. Unlike other membrane transport proteins, porins are large enough to allow passive diffusion. Studies have shown that VDAC1 is subject to both phosphorylation and acetylation (PMID: 23233904). The apparent molecular weight of VDAC1 is 30-37 kDa (PMID: 14573604; 23754752; 25681439). Hypoxic conditions were found to trigger cleavage of the VDAC1 C-terminal to yield a 26-kDa truncated but active form (PMID: 22389449; 23233904). This polyclonal antibody raised against full-length human VDAC1 protein can cross react with VDAC2. |
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