TGM2 Monoclonal antibody proteintech 68006-1-Ig
$449.00
In stock
SKU
68006-1-Ig
2D4C11, Erythrocyte transglutaminase, TG(C), TG2, TGase 2
| Host / Isotype: Mouse / IgG2a | Class: Monoclonal |
| Reactivity: Human And More (2) | Immunogen: CatNo: Ag7462 Product name: Recombinant human TGM2 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-349 aa of BC003551 Sequence: MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQP Predict reactive species |
| Applications: WB, IHC, IF/ICC, FC (Intra), CoIP, ELISA | Observed Molecular Weight: 77 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC003551 |
| Conjugate: Unconjugated | Gene Symbol: TGM2 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 7052 |
| Application: Western Blot (WB) | RRID: ENSG00000198959 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: AB_2918753 |
| Tested Reactivity: Human | Form: Unconjugated |
| Host / Isotype: Mouse / IgG2a | Background Information: Transglutaminase 2 (TGM2) is a ubiquitous and multifunctional calcium-dependent enzyme belonging to the transglutaminase family. It is best known for its canonical activity of catalyzing the cross-linking of proteins by forming stable ε-(γ-glutamyl)lysine isopeptide bonds, which contributes to extracellular matrix stabilization and wound healing. Beyond this, TGM2 exhibits GTPase activity, allowing it to function as a signaling G-protein in intracellular processes. It is implicated in a wide range of physiological functions, including cell adhesion, proliferation, and apoptosis, as well as pathological conditions such as celiac disease, fibrosis, neurodegenerative disorders, and cancer metastasis, where its dysregulated expression often contributes to disease progression. |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
