VCP Monoclonal antibody proteintech 60316-1-Ig
$449.00
In stock
SKU
60316-1-Ig
15S Mg(2+) ATPase p97 subunit, 15S Mg(2+)-ATPase p97 subunit, 2A4B10, EC:3.6.4.6, HEL-220
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: human, mouse | Immunogen: CatNo: Ag1002 Product name: Recombinant human VCP protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 345-644 aa of BC007562 Sequence: GMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNIGDGGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEIRRERERQTNPSAMEVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQTLQQSRGFGSFRFPSGNQGGAGPSQGSGGGTGGSVYTEDNDDDLYG Predict reactive species |
| Applications: WB, IHC, IF/ICC, FC (Intra), ChIP, ELISA | Observed Molecular Weight: 89 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC007562 |
| Conjugate: Unconjugated | Gene Symbol: VCP |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 7415 |
| Application: Western Blot (WB) | RRID: AB_2881427 |
| Dilution: WB : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: VCP(Valosin-containing protein), also known as TER ATPase and 15S Mg2+-ATPase p97 subunit, belongs to the AAA ATPase family. VCP was first identified as a result of attempts to clone a putative peptide hormone called valosin. It was found that the cloned cDNA encoded a ubiquitously expressed 90 kDa cytosolic protein, termed VCP, which showed none of the characteristics of a peptide hormone precursor(PMID:1382975). Defects in VCP are the cause of inclusion body myopathy with early-onset Paget disease and frontotemporal dementia (IBMPFD) and amyotrophic lateral sclerosis type 14 with or without frontotemporal dementia (ALS14). VCP has a calculated molecular weight of 89 kDa and an apparent molecular weight of 90-100 kDa (PMID: 15732117, 1382975). |
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