Hexokinase 1 Polyclonal antibody proteintech 19662-1-AP

$449.00
In stock
SKU
19662-1-AP

 

HK1, Hexokinase-A, Hexokinase-1, Hexokinase1, Hexokinase type I

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse, Rat And More (2) Immunogen: CatNo: Ag8015 Product name: Recombinant human HK1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 583-917 aa of BC008730 Sequence: SDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS Predict reactive species
 Applications: WB, IF/ICC, IP, ELISA Observed Molecular Weight: 102 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC008730
Conjugate: Unconjugated Gene Symbol: Hexokinase 1
Tested Applications: Positive WB detected in Gene ID (NCBI): 3098
Application: Western Blot (WB) RRID: AB_10859778
Dilution: WB : 1:2000-1:16000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: The hexokinases (HKs) catalyze the first obligatory step in glucose metabolism to generate glucose-6-phosphate. This not only furthers glucose entry by maintaining the concentration gradient for facilitated glucose influx but also provides the first intermediate for essentially all major pathways using glucose. There are four conventional HK isoforms, HK1/2/3/4, encoded by four different genes. Most adult tissues express only HK1. Muscle and adipose tissue use HK2 for glycolysis, liver, and pancreatic beta cells express HK4 (also called glucokinase) and do not express HK1 or HK2. (PMID: 31434645, PMID: 31848318)

 

 

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