SND1 Monoclonal antibody proteintech 60265-1-Ig

$449.00
In stock
SKU
60265-1-Ig

 

100 kDa coactivator, 1A6A4, EBNA2 coactivator p100, EC:3.1.31.1, p100

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: human, mouse, rat Immunogen: CatNo: Ag1200 Product name: Recombinant human SND1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 548-911 aa of BC017180 Sequence: TCLITFLLAGIECPRGARNLPGLVQEGEPFSEEATLFTKELVLQREVEVEVESMDKAGNFIGWLHIDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRADDADEFGYSR Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, CoIP, ELISA Observed Molecular Weight: 101 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC017180
Conjugate: Unconjugated Gene Symbol: SND1
Tested Applications: Positive WB detected in Gene ID (NCBI): 27044
Application: Western Blot (WB) RRID: AB_2881386
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Mouse / IgG1 Background Information: Staphylococcal nuclease domain-containing 1 (SND1), is a multifunctional nuclease that consists of four staphylococcal nuclease domains and a tudor domain. SND1 acts as a coactivator that facilitates transcriptional activity of STAT5, 6 and c-Myc. SND1 is a comprising part of the RNA-induced silencing complex(RISC), and takes part in the functions of miRNA, regulates transcription through transcriptional coactivation, RNA interference, RNA splicing, and RNA editing. Higher level of SND1 has been found in colon cancer and prostate cancer, can promote HCC angiogenesis in xenograft model through induction of angiogenic factors.

 

 

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