DFNA5/GSDME Polyclonal antibody proteintech 13075-1-AP
$449.00
In stock
SKU
13075-1-AP
DFNA5, Gasdermin E, Gasdermin-E, GSDME, deafness, autosomal dominant 5
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse And More (1) | Immunogen: CatNo: Ag3746 Product name: Recombinant human DFNA5 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 111-460 aa of BC019689 Sequence: SQSSFGTLRKQEVDLQQLIRDSAERTINLRNPVLQQVLEGRNEVLCVLTQKITTMQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIELYVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSVLKQATLLLERNFHPFAELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAVLGELKPRQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSAAALLGTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISL Predict reactive species |
| Applications: WB, IHC, IF, FC (Intra), IP, CoIP, ELISA | Observed Molecular Weight: 496 aa, 55 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC019689 |
| Conjugate: Unconjugated | Gene Symbol: DFNA5 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 1687 |
| Application: Western Blot (WB) | RRID: AB_2093053 |
| Dilution: WB : 1:1000-1:8000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: DFNA5 (deafness, autosomal dominant 5), also known as GSDME or ICERE-1, is a 496 amino acid protein that is expressed in cochlea tissue, as well as in placenta, brain, heart, liver, lung and pancreas. Defects in the gene encoding DFNA5 are the cause of non-syndromic sensorineural deafness autosomal dominant type 5 (DFNA5), a form of sensorineural hearing loss that results from damage to one of various structures that receive sound information in the brain. GSDME produced two GSDME fragments with MW of 35 kDa and 25 kDa. |
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