Claudin 1 Polyclonal antibody proteintech 28674-1-AP

$449.00
In stock
SKU
28674-1-AP

 

Caudin 1, CLDN1, Claudin-1, CLD1, ILVASC

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse, Rat And More (5) Immunogen: CatNo: Ag29269 Product name: Recombinant human Claudin 1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 102-211 aa of BC012471 Sequence: MKCMKCLEDDEVQKMRMAVIGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGALLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV Predict reactive species
 Applications: WB, IHC, IF/ICC, ELISA Observed Molecular Weight: 211 aa, 23 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC012471
Conjugate: Unconjugated Gene Symbol: Claudin 1
Tested Applications: Positive WB detected in Gene ID (NCBI): 9076
Application: Western Blot (WB) RRID: AB_2881190
Dilution: WB : 1:1000-1:6000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: Claudins are a family of proteins that are the most important components of tight junctions, where they establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. 23 claudins have been identified. They are small (20-27 kilodalton (kDa)) proteins with similar structures. They have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm. Claudin-1 is an integral membrane protein expressed primarily in keratinocytes and normal mammary epithelial cells. Claudin 1 forms tight junctions with other claudin proteins and plays an important role in the intestinal epithelial barrier.

 

 

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