IFITM2-Specific Monoclonal antibody proteintech 66137-1-Ig
$449.00
In stock
SKU
66137-1-Ig
IFITM2, 1 8D, 18D, 3D5F7, DSPA2c
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: human | Immunogen: Recombinant protein Predict reactive species |
| Applications: WB, IHC, IF, ELISA | Observed Molecular Weight: 15 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: IFITM2 |
| Conjugate: Unconjugated | Gene Symbol: 10581 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_2881536 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:500-1:2000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Mouse / IgG1 | Background Information: IFITM2, also named as 1-8D, belongs to the CD225 family. It is an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. IFITM2 induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. It is overexpressed in colon carcinoma. IFITM2 is a novel pro-apoptotic gene that will provide new insights into the regulated cellular pathways to death.(PMID:19544527) This antibody is specific to IFTIM2. |
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