ARL13B Monoclonal antibody proteintech 66739-1-Ig

$449.00
In stock
SKU
66739-1-Ig

 

ARL2-like protein 1, ARL2L1, ARL2 like protein 1, ADP-ribosylation factor-like protein 2-like 1, ADP-ribosylation factor-like protein 13B

Host / Isotype: Mouse / IgG2a Class: Monoclonal
Reactivity: Human, Mouse, Pig, Canine And More (1) Immunogen: CatNo: Ag12031 Product name: Recombinant human ARL13B protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-321 aa of BC094725 Sequence: MFSLMASCCGWFKRWREPVRLANKQDKEGALGEADVIECLSLEKLVNEHKCLCQIEPCSAISGYGKKIDKSIKKGLYWLLHVIARDFDALNERIQKETTEQRALEEQEKQERAERVRKLREERKQNEQEQAELDGTSGLAELDPEPTNPFQPIASVIIENEGKLEREKKNQKMEKDSDGCHLKHKMEHEQIETQGQVNHNGQKNNEFGLVENYKEALTQQLKNEDETDRPSLESANGKKKTKKLRMKRNHRVEPLNIDDCAPESPTPPPPPPPVGWGTPKVTRLPKLEPLGETHHNDFYRKPLPPLAVPQRPNSDAHDVIS Predict reactive species
 Applications: WB, IHC, IF/ICC, IF-Fro, ELISA Observed Molecular Weight: 48 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC094725
Conjugate: Unconjugated Gene Symbol: ARL13B
Tested Applications: Positive WB detected in Gene ID (NCBI): 200894
Application: Western Blot (WB) RRID: AB_2882088
Dilution: WB : 1:1000-1:6000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Pig, Canine Form: Liquid
Host / Isotype: Mouse / IgG2a Background Information: ARL13B, also named as ARL2L1, is a small ciliary G protein of the Ras superfamily. Localized in the cilia, it is required for cilium biogenesis and sonic hedgehog signaling. Defects in ARL13B are the cause of Joubert syndrome (JS) which is an autosomal recessive disorder characterized by a distinctive cerebellar malformation (PMID: 19906870). Arl13b is predicted to be a 48 kDa protein, and the 60 kDa band is likely to represent a modified form of Arl13b. ARL13B can be used to mark the cilia (PMID:22072986).

 

 

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