FGFR1 Monoclonal antibody proteintech 60325-1-Ig
$449.00
In stock
SKU
60325-1-Ig
bFGF R 1, BFGFR, bFGF-R-1, CD331, CEK
| Host / Isotype: Mouse / IgG2c | Class: Monoclonal |
| Reactivity: human | Immunogen: CatNo: Ag3646 Product name: Recombinant human FGFR1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 471-821 aa of BC018128 Sequence: LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR Predict reactive species |
| Applications: WB, IHC, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 820 aa, 91 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC018128 |
| Conjugate: Unconjugated | Gene Symbol: FGFR1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 2260 |
| Application: Western Blot (WB) | RRID: AB_2881435 |
| Dilution: WB : 1:1000-1:3000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG2c | Background Information: Fibroblast growth factor receptor 1 (FGFR1) is a tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors. FGFR1 has been implicated in diverse biological processes including embryonic development, cell proliferation, differentiation, migration, and tumorigenesis. Mutations in the FGFR1 gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer, and autosomal dominant Kallmann syndrome. Alternatively spliced variants that encode different protein isoforms have been described. |