IL-18 Monoclonal antibody proteintech 60070-1-Ig

$449.00
In stock
SKU
60070-1-Ig

 

IL18, Pre-IL18, 5C6F8, Iboctadekin, IFN-gamma-inducing factor

Host / Isotype: Mouse / IgG2b Class: Monoclonal
Reactivity: Human And More (1) Immunogen: CatNo: Ag1063 Product name: Recombinant human Pre IL-18 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-193 aa of BC007461 Sequence: MAAEPVEDNCINFVAMKFIDNTLYFIAEDDENLESDYFGKLESKLSVIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIISMYKDSQPRGMAVTISVKCEKISTLSCENKIISFKEMNPPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLFKLILKKEDELGDRSIMFTVQNED Predict reactive species
 Applications: WB, IHC, IF/ICC, IF-P, FC (Intra), ELISA Observed Molecular Weight: 193 aa, 22 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC007461
Conjugate: Unconjugated Gene Symbol: IL-18
Tested Applications: Positive WB detected in Gene ID (NCBI): 3606
Application: Western Blot (WB) RRID: AB_2280158
Dilution: WB : 1:2000-1:10000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Mouse / IgG2b Background Information: IL-18, is a proinflammatory cytokine involved in the development of Th1 cells and in immune response. It can stimulate the NK cells and certain T cells to release IFN gamma which plays an important role in activating the macrophages or other cells. IL18 has been demonstrated to have the potential to enhance Fas ligand-mediated cytotoxicity, which is increased in PE and regulates placental apoptosis. IL18 is synthesized as a 24 kDa precursor and then cleaved into a biologically activate 18 kDa form.

 

 

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