USP25 Monoclonal antibody proteintech 67769-1-Ig
$449.00
In stock
SKU
67769-1-Ig
Ubiquitin thiolesterase 25, Ubiquitin thioesterase 25, Ubiquitin carboxyl-terminal hydrolase 25, EC:3.4.19.12, Deubiquitinating enzyme 25
| Host / Isotype: Mouse / IgG2b | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: ubiquitin specific peptidase 25 |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 125 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: USP25 |
| Conjugate: Unconjugated | Gene Symbol: 29761 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_2918535 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purification |
| Host / Isotype: Monoclonal | Background Information: Ubiquitin carboxyl-terminal hydrolase 25, encoded by USP25 gene, has three isoforms by alternative splicing. Isoform USP25a is found in most adult and fetal tissues; Isoform USP25b is found in all tissues except heart and skeletal muscle. Isoform USP25m is heart and skeletal muscle specific, and is upregulated during myogenesis, therefore, may have a role in the regulation of muscular differentiation and function. USP25, as deubiquitinating enzyme that hydrolyzes ubiquitin moieties conjugated to substrates, functions to process newly synthesized Ubiquitin, to recycle ubiquitin molecules or to edit polyubiquitin chains and prevents proteasomal degradation of substrates. |