m6A Monoclonal antibody proteintech 68055-1-Ig
$449.00
In stock
SKU
68055-1-Ig
6-N-Methyladenoside, N6-methyladenosine
| Host / Isotype: Mouse / IgG3 | Class: Monoclonal |
| Reactivity: Chemical Compound, M6a And More (5) | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, IF, IP, ChIP, RIP, Dot Blot, ELISA | Observed Molecular Weight: m6A |
| Formulation: PBS, Azide, Glycerol | |
| Conjugate: Unconjugated | Gene Symbol: AB_2918796 |
| Tested Applications: Positive RIP detected in | Gene ID (NCBI): Unconjugated |
| Application: RIP | RRID: Liquid |
| Dilution: RIP : 5-10μg antibody/mg lysate | Conjugate: Protein A purification |
| Tested Reactivity: Chemical Compound, M6a | Form: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Host / Isotype: Mouse / IgG3 | Background Information: m6A (N6-methyladenosine) is the most abundant internal modification in mammalian mRNA. This modification is installed by the m6A methyltransferases or termed "writers"such as METTL3 and METTL14, and can be reversed by demethylases that serve as "erasers" such as FTO and ALKBH5. The stability of m6A-modified mRNA is regulated by m6A reader protein YTHDFs, which recognizes m6A and reduces the stability of target transcripts. m6A modification and its regulatory proteins play critical roles in cancer pathogenesis and progression. m6A modification is also invovled in viruses life cycles, suggesting that drugs targets to m6A pathway could be used for antiviral thereapy. Protocol for Dot Blot: https://www.ptglab.com/protocol/68055-1-IgDotBlot.pdf |
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