CYP27A1 Polyclonal antibody proteintech 14739-1-AP

$449.00
In stock
SKU
14739-1-AP

 

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse, Rat And More (3) Immunogen: CatNo: Ag6408 Product name: Recombinant human CYP27A1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 183-531 aa of BC051851 Sequence: DDFMTRLDQLRAESASGNQVSDMAQLFYYFALEAICYILFEKRIGCLQRSIPEDTVTFVRSIGLMFQNSLYATFLPKWTRPVLPFWKRYLDGWNAIFSFGKKLIDEKLEDMEAQLQAAGPDGIQVSGYLHFLLASGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPETGELKSVARIVLVPNKKVGLQFLQRQC Predict reactive species
 Applications: WB, IHC, IF, ELISA Observed Molecular Weight: 60 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC051851
Conjugate: Unconjugated Gene Symbol: CYP27A1
Tested Applications: Positive WB detected in Gene ID (NCBI): 1593
Application: Western Blot (WB) RRID: AB_2089276
Dilution: WB : 1:500-1:1000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: Mitochondrial sterol 27-hydroxylase (CYP27A1) catalyzes oxidative cleavage of the sterol side chain in the bile acid biosynthetic pathway in the liver and 27-hydroxylation of cholesterol in most tissues(PMID:17088262). It belongs to the cytochrome P450 family. CYP27A1 catalyses an important sterol elimination pathway in the macrophage, and consequently may protect against atherosclerosis.

 

 

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