IFT88 Polyclonal antibody proteintech 13967-1-AP

$449.00
In stock
SKU
13967-1-AP

 

TTC10, TG737, Intraflagellar transport protein 88 homolog

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse, Rat, Canine And More (3) Immunogen: CatNo: Ag4980 Product name: Recombinant human IFT88 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 532-833 aa of BC030776 Sequence: NIGLTYEKLNRLDEALDCFLKLHAILRNSAEVLYQIANIYELMENPSQAIEWLMQVVSVIPTDPQVLSKLGELYDRGGDKSQAFQYYYESYRYFPCNIEVIEWLGAYYIDTQFWEKAIQYFERASLIQPTQVKWQLMVASCFRRSGNYQKALDTYKDTHRKFPENVECLRFLVRLCTDLGLKDAQEYARKLKRLEKMKEIREQRIKSGRDGSGGSRGKREGSASGDSGQNYSASSKGERLSARLRALPGTNEPYESSSNKEIDASYVDPLGPQIERPKTAAKKRIDEDDFADEELGDDLLPE Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, CoIP, ELISA Observed Molecular Weight: 94 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC030776
Conjugate: Unconjugated Gene Symbol: IFT88
Tested Applications: Positive WB detected in Gene ID (NCBI): 8100
Application: Western Blot (WB) RRID: AB_2121979
Dilution: WB : 1:2000-1:12000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat, Canine Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: Intraflagellar transport (IFT), mediated by molecular motors and IFT particles, is an important transport process that occurs in the cilium and has been shown to be essential for the assembly and maintenance of cilia and flagella in many organisms. IFT88 (intraflagellar transport protein 88; also known as TG737 or TTC10) is a component of IFT particles and required for cilium biogenesis. Defects in IFT88/Tg737 lead to polycystic kidney disease (11062270). IFT88 localizes to spindle poles during mitosis and is required for spindle orientation in mitosis (21441926). This antibody was raised against the C-terminal region of human IFT88 and can detect the endogenous level of IFT88.

 

 

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