INSR/CD220 Polyclonal antibody proteintech 20433-1-AP
$449.00
In stock
SKU
20433-1-AP
INSR, CD220, EC:2.7.10.1, HHF5, insulin receptor
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human And More (6) | Immunogen: CatNo: Ag13922 Product name: Recombinant human INSR protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 968-1370 aa of BC117172 Sequence: RKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMENVPLDRSSHCQREEAGGRDGGSSLGFKRSYEEHIPYTHMNGGKKNGRILTLPRSNPS Predict reactive species |
| Applications: WB, IHC, IF, IP, CoIP, Dot blot, ELISA | Observed Molecular Weight: 1382 aa, 156 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC117172 |
| Conjugate: Unconjugated | Gene Symbol: INSR |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 3643 |
| Application: Western Blot (WB) | RRID: AB_10646469 |
| Dilution: WB : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: The biological effects of INS are mediated by a membrane-spanning cell surface receptor that has been shown to consist of disulfide-linked alpha-subunits (135 kDa) and beta-subunits (95 kDa) that are cleaved products of a common precursor. The binding of INS to the receptor extracellular domain results in intracellular activation of a tyrosine-specific kinase activity and the generation of signals that determine the cellular response (PMID: 2369896). This antibody raised against 980-1382aa of human INS receptor can recognize full-length INS receptor precursor and INS receptor beta subunit. |
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