FcZero-rAb? APC Anti-Mouse Nectin-2/CD112 Rabbit Recombinant Antibody Proteintech APC-FcA98231

$299.00
In stock
SKU
APC-FcA98231

 

CD112, Herpes virus entry mediator B, HveB, mHveB, Mph

Formulation::PBS, Azide, BSA Formulation::PBS, Azide, BSA1
Applications:Flow Cytometry (FC) (INTRA) Formulation::PBS, Azide, BSA2
 Reactivity:Rabbit / IgG Formulation::PBS, Azide, BSA3
Type:CatNo: Eg2019 Product name: Recombinant Mouse Nectin-2/CD112 protein (rFc Tag) Source: mammalian cells-derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 32-351 aa of NM_008990.3 Sequence: QDVRVRVLPEVRGRLGGTVELPCHLLPPTTERVSQVTWQRLDGTVVAAFHPSFGVDFPNSQFSKDRLSFVRARPETNADLRDATLAFRGLRVEDEGNYTCEFATFPNGTRRGVTWLRVIAQPENHAEAQEVTIGPQSVAVARCVSTGGRPPARITWISSLGGEAKDTQEPGIQAGTVTIISRYSLVPVGRADGVKVTCRVEHESFEEPILLPVTLSVRYPPEVSISGYDDNWYLGRSEAILTCDVRSNPEPTDYDWSTTSGVFPASAVAQGSQLLVHSVDRMVNTTFICTATNAVGTGRAEQVILVRESPSTAGAGATGG Predict reactive species Formulation::PBS, Azide, BSA4
RRID:19294 Formulation::PBS, Azide, BSA5
Storage Buffer:Protein A purification Formulation::PBS, Azide, BSA6
Background Information:Nectin 2, also named as PVRL2, CD112, HVEB, PRR2 and PVRR2, is an adhesion molecule widely expressed in cell lines of different lineages, including hematopoietic, neuronal, endothelial and epithelial cells. CD112 belongs to a new family of immunoglobulin-like molecules that includes four members (CD111, CD112, PRR3 and CD155) sharing an ectodomain made of three Ig domains, of V and C types. CD112 is expressed in the myelo-monocytic and megakaryocytic hematopoietic lineages and the function in hematopoiesis is currently unknown. CD112 is an intercellular homophilic adhesion. CD112 localizes specifically at adherents junctions via its cytoplasmic interaction with the scaffold F-actin binding protein afadin. Disruption of the murine CD112 gene leads to infertility of male mice with morphologically aberrant spermatozoa. CD112 mediates entry of some alphaherpesvirus mutants (also named HveB) via its V domain. CD112 is involved in cell to cell spreading of viruses. Formulation::PBS, Azide, BSA7
biogegep8 Formulation::PBS, Azide, BSA8
biogegep9 Formulation::PBS, Azide, BSA9
Formulation::PBS, Azide, BSA0 Applications:Flow Cytometry (FC) (INTRA)0

 

 

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