Anti-Human CD11c (3.9) Mouse IgG2a Recombinant Antibody Proteintech 65568-1-MR
$299.00
In stock
SKU
65568-1-MR
3.9, CD11 antigen-like family member C, Integrin alpha X, Integrin alpha-X, ITGAX
| Formulation::PBS, Azide | Formulation::PBS, Azide1 |
| Applications:Flow Cytometry (FC) | Formulation::PBS, Azide2 |
| Reactivity:Mouse / IgG2a | Formulation::PBS, Azide3 |
| Type:Rheumatoid synovial cells and human monocytes Predict reactive species | Formulation::PBS, Azide4 |
| RRID:3687 | Formulation::PBS, Azide5 |
| Storage Buffer:Liquid | Formulation::PBS, Azide6 |
| Background Information:Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α/β heterodimer with CD18 (integrin β2). CD11c/CD18 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533). | Formulation::PBS, Azide7 |
| biogegep8 | Formulation::PBS, Azide8 |
| biogegep9 | Formulation::PBS, Azide9 |
| Formulation::PBS, Azide0 | Applications:Flow Cytometry (FC)0 |