Cathepsin B Polyclonal antibody Proteintech 12216-1-AP
$299.00
In stock
SKU
12216-1-AP
CTSB, APP secretase, APPS, Cat B, Cathepsin B heavy chain
| Formulation::PBS, Azide, Glycerol | Formulation::PBS, Azide, Glycerol1 |
| Applications:Western Blot (WB) | Formulation::PBS, Azide, Glycerol2 |
| Reactivity:Human, Mouse, Rat, Pig, Zebrafish, Bovine, Frog | Formulation::PBS, Azide, Glycerol3 |
| Type:Antibody | Formulation::PBS, Azide, Glycerol4 |
| RRID:BC010240 | Formulation::PBS, Azide, Glycerol5 |
| Storage Buffer:Unconjugated | Formulation::PBS, Azide, Glycerol6 |
| Background Information:CTSB(Cathepsin B) is also named as CPSB and belongs to the peptidase C1 family. It participates in intracellular degradation and turnover of proteins. Cathepsin B precursors found in human malignant ascites fluid do not possess mannose-rich carbohydrates suggesting that a defect in the post translational processing of carbohydrate moieties on tumor. Cathepsin B exists as both glycosylated and unglycosylated forms(PMID:1637335). In rat macrophages and hepatocytes pro- cathepsin B is 39 kDa (unglycosylated =35 kDa), whereas in human fibroblasts procathepsin B is 44.5-46kDa (unglycosylated=39kDa)(PMID:2097084). It can be detected the 43 kDa form of pro-CTSB, 31 kDa and 25 kDa mature forms in mouse brain by western blot(PMID:20616152). | Formulation::PBS, Azide, Glycerol7 |
| biogegep8 | Formulation::PBS, Azide, Glycerol8 |
| biogegep9 | Formulation::PBS, Azide, Glycerol9 |
| Formulation::PBS, Azide, Glycerol0 | Applications:Western Blot (WB)0 |