Anti-Human EMR2/CD312 Rabbit Recombinant Antibody Proteintech 98260-1-RR
$299.00
In stock
SKU
98260-1-RR
EMR2, EGF-like module receptor 2, EGF like module receptor 2, CD312, Adhesion G protein-coupled receptor E2
| Formulation::PBS, Azide | Formulation::PBS, Azide1 |
| Applications:Flow Cytometry (FC) | Formulation::PBS, Azide2 |
| Reactivity:Rabbit / IgG | Formulation::PBS, Azide3 |
| Type:Recombinant protein Predict reactive species | Formulation::PBS, Azide4 |
| RRID:30817 | Formulation::PBS, Azide5 |
| Storage Buffer:Q9UHX3-1 | Formulation::PBS, Azide6 |
| Background Information:EMR2 (Epidermal Growth Factor-like module-containing Mucin-like Hormone Receptor 2), also known as CD312 or ADGRE2, is a member of the adhesion-GPCR family that contains extracellular EGF-like domains. EMR2 contains a total of five tandem EGF-like domains and expresses similar protein isoforms consisting of various numbers of EGF-like domains as a result of alternative RNA splicing (PMID: 10903844). EMR2 is restricted to myeloid cells including monocytes, macrophages, dendritic cells and granulocytes28 and its expression is highly regulated during monocyte/macrophage differentiation (PMID: 31969668).The ligation of EMR2 could increase neutrophil adhesion, migration and anti-microbial mediator production and could enhance the systemic inflammation (PMID: 27905560). | Formulation::PBS, Azide7 |
| biogegep8 | Formulation::PBS, Azide8 |
| biogegep9 | Formulation::PBS, Azide9 |
| Formulation::PBS, Azide0 | Applications:Flow Cytometry (FC)0 |