MMP1 Recombinant monoclonal antibody Proteintech 83114-2-RR

$299.00
In stock
SKU
83114-2-RR

 

22 kDa interstitial collagenase, 230343G1, 27 kDa interstitial collagenase, CLG, CLGN

Formulation::PBS, Azide, Glycerol Formulation::PBS, Azide, Glycerol1
Applications:Western Blot (WB) Formulation::PBS, Azide, Glycerol2
 Reactivity:Human Formulation::PBS, Azide, Glycerol3
Type:Antibody Formulation::PBS, Azide, Glycerol4
RRID:BC013875 Formulation::PBS, Azide, Glycerol5
Storage Buffer:Unconjugated Formulation::PBS, Azide, Glycerol6
Background Information:MMP1, also named as CLG, belongs to the peptidase M10A family. MMP is the main enzyme that cleaves fibrillar collagen, namely types I, II, III, VII, and X.It is involved in cell migration and invasion, and is frequently up-regulated in cancer cells. It can be cleavage to two major forms (22 kDa and 27 kDa) by undergoing autolytic,and the minor form (25 kDa) is the glycosylated form of the 22 kDa form. The 27 kDa form has no activity while the 22/25 kDa form can act as activator for collagenase.The sizes of pro-MMP-1 and active MMP-1 from human synovial fibroblasts have been reported as 52 to 56 kDa, depending on glycosylation, and 41 to 45 kDa, respectively.In addition ,a band of 62-kDa observed in the current study is pro-MMp-1(PMID:9418730). Formulation::PBS, Azide, Glycerol7
biogegep8 Formulation::PBS, Azide, Glycerol8
biogegep9 Formulation::PBS, Azide, Glycerol9
Formulation::PBS, Azide, Glycerol0 Applications:Western Blot (WB)0

 

 

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