Phospho-Histone H2A.X (Ser139) Recombinant monoclonal antibody Proteintech 83307-2-RR

$299.00
In stock
SKU
83307-2-RR

 

H2A.X (Ser139), H2A.X P-S139, H2A.X Ser139, H2A.XS139, H2A.XS139Ph

Formulation::PBS, Azide, Glycerol Formulation::PBS, Azide, Glycerol1
Applications:Western Blot (WB) Formulation::PBS, Azide, Glycerol2
 Reactivity:Human Formulation::PBS, Azide, Glycerol3
Type:Antibody Formulation::PBS, Azide, Glycerol4
RRID:BC013416 Formulation::PBS, Azide, Glycerol5
Storage Buffer:Unconjugated Formulation::PBS, Azide, Glycerol6
Background Information:The histone variant H2AX is a major component of the DNA damage response (DDR), especially functioning in amplifying DNA damage signals. In response to DNA double-strand breaks (DSBs), H2AX is instantaneously phosphorylated at Ser139 (a form called cH2AX) by the kinases ATM and ATR. The phosphorylation of H2AX at Ser139, resulting in the formation of gamma-H2AX puncta in the nuclei, is an early event in the cellular response to DNA damage. Therefore, phospho-Histone H2A. X (Ser139) is also known as γH2AX. The phosphorylation site of H2AX, Ser139, has also been described as Ser140 in other literature, and they recognize the same amino acid site. (PMID: 22908299, PMID: 30106130, PMID:22941631) Formulation::PBS, Azide, Glycerol7
biogegep8 Formulation::PBS, Azide, Glycerol8
biogegep9 Formulation::PBS, Azide, Glycerol9
Formulation::PBS, Azide, Glycerol0 Applications:Western Blot (WB)0

 

 

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