Caspase 3/P17/P19 Recombinant monoclonal antibody Proteintech 82202-1-RR
$299.00
In stock
SKU
82202-1-RR
CASP3, Caspase3, 5G20, CASP 3, CASP-3
| Formulation::PBS, Azide, Glycerol | Formulation::PBS, Azide, Glycerol1 |
| Applications:Western Blot (WB) | Formulation::PBS, Azide, Glycerol2 |
| Reactivity:Human, Mouse, Rat, Rabbit, Bovine | Formulation::PBS, Azide, Glycerol3 |
| Type:Antibody | Formulation::PBS, Azide, Glycerol4 |
| RRID:NM_004346 | Formulation::PBS, Azide, Glycerol5 |
| Storage Buffer:Unconjugated | Formulation::PBS, Azide, Glycerol6 |
| Background Information:Caspases, a family of endoproteases, are critical players in cell regulatory networks controlling inflammation and cell death. Initiator caspases (caspase-2, -8, -9, -10, -11, and -12) cleave and activate downstream effector caspases (caspase-3, -6, and -7), which in turn execute apoptosis by cleaving targeted cellular proteins. Caspase 3 (also named CPP32, SCA-1, and Apopain) proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at the beginning of apoptosis. Caspase 3 plays a key role in the activation of sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Caspase 3 can also form heterocomplex with other proteins and performs the molecular mass of 50-70 kDa. This antibody can recognize p17, p19 and p32 of Caspase 3. | Formulation::PBS, Azide, Glycerol7 |
| biogegep8 | Formulation::PBS, Azide, Glycerol8 |
| biogegep9 | Formulation::PBS, Azide, Glycerol9 |
| Formulation::PBS, Azide, Glycerol0 | Applications:Western Blot (WB)0 |