Lamin B1 Polyclonal antibody Proteintech 12987-1-AP

$299.00
In stock
SKU
12987-1-AP

 

LMNB1, laminB1, Lamin-B1, LMN2, LMNB

Formulation::PBS, Azide, Glycerol Formulation::PBS, Azide, Glycerol1
Applications:Western Blot (WB) Formulation::PBS, Azide, Glycerol2
 Reactivity:Human, Mouse, Rat, Pig, Canine, Monkey, Chicken, Hamster, Escherichia Coli, Bombyx Mori Formulation::PBS, Azide, Glycerol3
Type:Antibody Formulation::PBS, Azide, Glycerol4
RRID:BC012295 Formulation::PBS, Azide, Glycerol5
Storage Buffer:AB_2136290 Formulation::PBS, Azide, Glycerol6
Background Information:Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Expression of uncleavable mutant lamin A or B caused significant delays in the onset of chromatin condensation and nuclear shrinkage during apoptosis (PMID:11953316). This protein is not suitable for samples where the nuclear envelope has been removed. Formulation::PBS, Azide, Glycerol7
biogegep8 Formulation::PBS, Azide, Glycerol8
biogegep9 Formulation::PBS, Azide, Glycerol9
Formulation::PBS, Azide, Glycerol0 Applications:Western Blot (WB)0

 

 

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