Anti-Human CD45RO (UCHL1) Mouse IgG2a Recombinant Antibody Proteintech 65613-1-MR
$299.00
In stock
SKU
65613-1-MR
CD45, EC:3.1.3.48, GP180, L CA, LCA
| Formulation::PBS, Azide | Formulation::PBS, Azide1 |
| Applications:Immunohistochemistry (IHC) | Formulation::PBS, Azide2 |
| Reactivity:Mouse / IgG2a | Formulation::PBS, Azide3 |
| Type:IL-2 dependent T cell line, CA1 Predict reactive species | Formulation::PBS, Azide4 |
| RRID:ENSG00000081237 | Formulation::PBS, Azide5 |
| Storage Buffer:Protein A purification | Formulation::PBS, Azide6 |
| Background Information:CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097). CD45 exists as multiple isoforms due to alternative splicing of three exons (4, 5, and 6, designated A, B, and C) in the extracellular domain (PMID: 12414720). CD45RO is the shortest CD45 isoform (lacking all three exons) and is expressed by activated and memory T cells, thymocytes, some B cells, and weakly on granulocytes and macrophage (PMID: 27100180; 12414720). | Formulation::PBS, Azide7 |
| biogegep8 | Formulation::PBS, Azide8 |
| biogegep9 | Formulation::PBS, Azide9 |
| Formulation::PBS, Azide0 | Applications:Immunohistochemistry (IHC)0 |