CDC25C Polyclonal antibody proteintech 16485-1-AP
$449.00
In stock
SKU
16485-1-AP
CDC25, EC:3.1.3.48, M phase inducer phosphatase 3, M-phase inducer phosphatase 3
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human And More (1) | Immunogen: CatNo: Ag9607 Product name: Recombinant human CDC25C protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-279 aa of BC019089 Sequence: MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANLSILSGGTPKCCLDLSNLSSGEITATQLTTSADLDETGHLDSSGLQEVHLAGMNHDQHLMKCSPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGLCLKKTVSLCDITITQMLEEDSNQ Predict reactive species |
| Applications: WB, IHC, IF, IP, ELISA | Observed Molecular Weight: 473 aa, 53 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC019089 |
| Conjugate: Unconjugated | Gene Symbol: CDC25C |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 995 |
| Application: Western Blot (WB) | RRID: AB_2291330 |
| Dilution: WB : 1:2000-1:16000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: The cell division cycle 25 (CDC25) family of proteins are highly conserved dual specificity phosphatases that activate cyclin-dependent kinase (CDK) complexes, which in turn regulate progression through the cell division cycle. CDC25C(cell division cycle 25 homolog C) is one of the 3 isoforms of CDC25 in mammalian cells. It is present in the cytoplasm of asynchronously growing human cells(PMID:10330186). And it may be phosphorylated by its own substrate, an active cdc2-cyclin B complex, to create an autoactivation loop(PMID:7937793). It can be hyperphosphorylated to get the active form of 70 kDa(PMID:18296513). CDC25C has some isofroms with molecular mass of 46-53 kDa. |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
