Specific Adeno-associated Virus
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Specific Adeno-associated Virus
Specific Adeno-associated Virus
It has been found in study that AAV has multiple serotypes.The main difference between various different serotypes of AAV vectors is the difference in capsid protein, so transfection efficiency of different serotypes in different tissues and cells are differential.
Tissue-specific promoters are also called organ-specific promoters. Under the action of such a promoter, the expression of a gene is commonly confined to some particular tissue or organ, and at the same time it exhibits developmental regulation and other properties. In this way, the waste caused by non-specific, continuous and efficient expression of foreign genes activated by constitutive promoters can be overcome and the effect of gene regulation can be increased.
Therefore, selecting appropriate serotypes with specific promoters for different tissues and organs enables targeted and efficient infection.
AAV serotypes for Different tissues
Tissue-specific promoters
AAV serotypes for specific tissues
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