TRX2/TXN2 Polyclonal antibody proteintech 13089-1-AP
$449.00
In stock
SKU
13089-1-AP
TRX2, MT TRX, MTRX, Mt-Trx, Thioredoxin 2
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human And More (2) | Immunogen: CatNo: Ag3640 Product name: Recombinant human TRX2,TXN2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-166 aa of BC013726 Sequence: MAQRLLLRRFLASVISRKPSQGQWPPLTSRALQTPQCSPGGLTVTPNPARTIYTTRISLTTFNIQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKKLIG Predict reactive species |
| Applications: WB, IHC, IF, ELISA | Observed Molecular Weight: 166 aa, 18 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC013726 |
| Conjugate: Unconjugated | Gene Symbol: Thioredoxin 2 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 25828 |
| Application: Western Blot (WB) | RRID: AB_2304119 |
| Dilution: WB : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: TXN2 (Thioredoxin-2) is also named as TRX2, MTRX, Mt-TRX and regulates the mitochondrial redox state and plays an important role in cell proliferation. It has been shown that cells conditionally deficient in Trx2 undergo apoptosis in the absence of exogenous stress, accompanied by an accumulation of intracellular ROS, the activation of caspase 9 and caspase 3, and the release of cytochrome c into the cytosol. In the retina, the expression profile and the role of Trx2 have not yet been defined (PMID: 18441302). |