Emerin Polyclonal antibody proteintech 10351-1-AP
$449.00
In stock
SKU
10351-1-AP
EMD, EDMD, LEMD5, STA
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: human, mouse | Immunogen: CatNo: Ag0236 Product name: Recombinant human EMD protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 66-252 aa of BC000738 Sequence: STRGDADMYDLPKKEDALLYQSKGYNDDYYEESYFTTRTYGEPESAGPSRAVRQSVTSFPDADAFHHQVHDDDLLSSSEEECKDRERPMYGRDSAYQSITHYRPVSASRSSLDLSYYPTSSSTSFMSSSSSSSSWLTRRAIRPENRAPGAGLGQDRQVPLWGQLLLFLVFVIVLFFIYHFMQAEEGN Predict reactive species |
| Applications: WB, IHC, IF/ICC, FC (Intra), IP, CoIP, ELISA | Observed Molecular Weight: 34 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC000738 |
| Conjugate: Unconjugated | Gene Symbol: EMD |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 2010 |
| Application: Western Blot (WB) | RRID: AB_2100056 |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: Emerin (Emery-Dreifuss muscular dystrophy) (EMD or EDMD), a serine-rich nuclear membrane protein, is a member of the nuclear lamina-associated protein family. EMD may mediate membrane anchorage to the cytoskeleton by stabilizing and promoting the formation of a nuclear actin cortical network. Defects in EMD gene are the cause of Emery-Dreifuss muscular dystrophy type 1 (EDMD1), a degenerative myopathy characterized by weakness and atrophy of muscle without involvement of the nervous system, early contractures of the elbows Achilles tendons and spine, and cardiomyopathy associated with cardiac conduction defects. EMD inhibits beta-catenin activity by preventing its accumulation in the nucleus and is involved in HIV-1 infection. |
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