CD31 Polyclonal antibody proteintech 11265-1-AP
$449.00
In stock
SKU
11265-1-AP
PECAM1, PECAM 1, PECA1, GPIIA', GPIIA
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human And More (5) | Immunogen: CatNo: Ag1787 Product name: Recombinant human CD31 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 428-738 aa of BC022512 Sequence: EVRCESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKANKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAPWKKGLIAVVIIGVIIALLIIAAKCYFLRKAKAKQMPVEMSRPAVPLLNSNNEKMSDPNMEANSHYGHNDDVGNHAMKPINDNKEPLNSDVQYTEVQVSSAESHKDLGKKDTETVYSEVRKAVPDAVESRYSRTEGSLDGT Predict reactive species |
| Applications: WB, IHC, IF/ICC, IF-P, IP, ELISA | Observed Molecular Weight: 83 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC022512 |
| Conjugate: Unconjugated | Gene Symbol: CD31 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 5175 |
| Application: Western Blot (WB) | RRID: ENSG00000261371 |
| Dilution: WB : 1:2000-1:10000 | Conjugate: AB_2299349 |
| Tested Reactivity: Human | Form: Unconjugated |
| Host / Isotype: Rabbit / IgG | Background Information: Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489). |
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