MYLK Polyclonal antibody proteintech 21642-1-AP
$449.00
In stock
SKU
21642-1-AP
EC:2.7.11.18, Kinase-related protein, KRP, MLCK, MLCK1
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse, Rat And More (2) | Immunogen: CatNo: Ag16306 Product name: Recombinant human MYLK protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1748-1914 aa of BC113456 Sequence: TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE Predict reactive species |
| Applications: WB, IHC, IF/ICC, IF-P, CoIP, ELISA | Observed Molecular Weight: 1914 aa, 211 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC113456 |
| Conjugate: Unconjugated | Gene Symbol: MYLK |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 4638 |
| Application: Western Blot (WB) | RRID: AB_10734590 |
| Dilution: WB : 1:500-1:2400 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: MYLK(Myosin light chain kinase) is also named as MLCK, MLCK1, MYLK1 and belongs to the protein kinase superfamily. It is a key enzyme in muscle contraction. Its activation is sufficient to enhance paracellular permeability and is required for tight junction barrier regulation in response to Na+-nutrient cotransport, inflammatory cytokines, or pathogenic bacteria(PMID:20404178). The expression of smooth muscle MYLK is tissue-specific. Smooth muscle MYLK generates three different proteins, long MYLK, short MYLK, and telokin. The 130-kDa smooth muscle, or short, MYLK (130 kDa) is expressed in smooth muscles. It has 8 isoforms produced by alternative splicing and alternative initiation and our anti-MYLK antibody can recognize these isforms. |
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