Cyclin D3 Polyclonal antibody proteintech 26755-1-AP
$449.00
In stock
SKU
26755-1-AP
CCND3, cyclin D, Cyclin D3, G1/S specific cyclin D3
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: human, rat and More (2) | Immunogen: CatNo: Ag25151 Product name: Recombinant human Cyclin D3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 250-292 aa of BC011616 Sequence: ALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL Predict reactive species |
| Applications: WB, IHC, IF/ICC, IP, ELISA | Observed Molecular Weight: 33 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC011616 |
| Conjugate: Unconjugated | Gene Symbol: Cyclin D3 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 896 |
| Application: Western Blot (WB) | RRID: ENSG00000112576 |
| Dilution: WB : 1:500-1:2000 | Conjugate: AB_2756524 |
| Tested Reactivity: human, rat | Form: Unconjugated |
| Host / Isotype: Rabbit / IgG | Background Information: Cyclin D3 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. |
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