CYC1 Polyclonal antibody proteintech 10242-1-AP
$449.00
In stock
SKU
10242-1-AP
Complex III subunit 4, Complex III subunit IV, CYC1, cytochrome c 1, UQCR4
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse And More (3) | Immunogen: CatNo: Ag0291 Product name: Recombinant human CYC1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 46-271 aa of BC001006 Sequence: ALSSKSGLSRGRKVMLSALGMLAAGGAGLAVALHSAVSASDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCASCHSMDFVAYRHLVGVCYTEDEAKELAAEVEVQDGPNEDGEMFMRPGKLFDYFPKPYPNSEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIAMAPPIYTDVLEFDDGTPATMSQIAKDVC Predict reactive species |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 35 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC001006 |
| Conjugate: Unconjugated | Gene Symbol: CYC1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 1537 |
| Application: Western Blot (WB) | RRID: AB_2090144 |
| Dilution: WB : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: CYC1, also named as Cytochrome c-1, belongs to the cytochrome c family. Cytochrome c1 is one respiratory subunit of the 11 subunits of the cytochrome bc1 complex of the mitochondrial electron-transfer chain. It mediates the transfer of an electron from Rieske iron-sulfur protein to cytochrome c(PMID:3036122 ). CYC1 mediates apoptosis. In this pathway, a variety of apoptotic stimuli cause CYC1 release from mitochondria, which in turn induces a series of biochemical reactions that result incaspase activation and subsequent cell death.(PMID:15189137) While CYC1 release and DNA fragmentation are unaffected by the noncleavablep75 mutant, mitochondrial morphology of dying cells is maintained, and loss of plasma membrane integrity is delayed(PMID:15186778). The protein migrated as a 35 kd band in SDS page. |
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