LATS2-Specific Polyclonal antibody proteintech 20276-1-AP
$449.00
In stock
SKU
20276-1-AP
LATS2, EC:2.7.11.1, KPM, LATS 2, Serine/threonine-protein kinase kpm
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: human, mouse | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, IF/ICC, IP, CoIP, ELISA | Observed Molecular Weight: 120 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_014572 |
| Conjugate: Unconjugated | Gene Symbol: LATS2 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 26524 |
| Application: Western Blot (WB) | RRID: AB_10697657 |
| Dilution: WB : 1:1000-1:8000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: LATS2, also named as KPM, belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. LATS2 is a tumor suppressor which plays a critical role in centrosome duplication, maintenance of mitotic fidelity and genomic stability. It negatively regulates G1/S transition by down-regulating cyclin E/CDK2 kinase activity. It is a negative regulator of the androgen receptor. LATS2 has a calculated molecular mass of 120 kDa and an apparent molecular mass of 150 kDa (PMID: 10871863). The antibody is specific to LATS2. |