Integrin alpha-5/CD49e Polyclonal antibody proteintech 10569-1-AP
$449.00
In stock
SKU
10569-1-AP
Integrin Alpha-5, ITGA5, CD49 antigen-like family member E, CD49e, FNRA
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse, Monkey And More (1) | Immunogen: CatNo: Ag0860 Product name: Recombinant human Integrin alpha-5 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 749-1049 aa of BC008786 Sequence: FTVPHLRDTKKTIQFDFQILSKNLNNSQSDVVSFRLSVEAQAQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDLGPAVHHVYELINQGPSSISQGVLELSCPQALEGQQLLYVTRVTGLNCTTNHPINPKGLELDPEGSLHHQQKREAPSRSSASSGPQILKCPEAECFRLRCELGPLHQQESQSLQLHFRVWAKTFLQREHQPFSLQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAILFGLLLLGLLIYILYKLGFFKRSLPYGTAMEKAQLKPPATSDA Predict reactive species |
| Applications: WB, IHC, IF, ELISA | Observed Molecular Weight: 115 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC008786 |
| Conjugate: Unconjugated | Gene Symbol: Integrin alpha 5 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 3678 |
| Application: Western Blot (WB) | RRID: AB_2130060 |
| Dilution: WB : 1:1000-1:8000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Monkey | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated alpha and beta subunits. Integrin alpha 5 (ITGA5), belongs to the integrin alpha chain family, primarily binds to Integrin beta 1 (ITGB1) to form an α5β1 heterodimer (PMID: 33711961). Integrin α5β1 is a specific receptor of fibronectin through its arginine-glycine-aspartic acid (RGD) binding site (PMID: 19608542). Integrin α5β1 plays roles in cell adhesion, migration and matrix formation, and has emerged as an essential mediator in many human carcinomas (PMID: 33408483). |
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