DDRGK1 Polyclonal antibody proteintech 21445-1-AP

$449.00
In stock
SKU
21445-1-AP

 

C20orf116, Dashurin, DDRGK domain containing 1, DDRGK domain-containing protein 1, UFBP1

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse, Rat And More (2) Immunogen: CatNo: Ag13742 Product name: Recombinant human DDRGK1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-314 aa of BC000643 Sequence: MVAPVWYLVAAALLVGFILFLTRSRGRAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGLRTQDTINRIQDLLAEGTITGVIDDRGKFIYITPEELAAVANFIRQRGRVSIAELAQASNSLIAWGRESPAQAPA Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, CoIP, ELISA Observed Molecular Weight: 314 aa, 36 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC000643
Conjugate: Unconjugated Gene Symbol: DDRGK1
Tested Applications: Positive WB detected in Gene ID (NCBI): 65992
Application: Western Blot (WB) RRID: AB_2827383
Dilution: WB : 1:2000-1:10000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: DDRGK1, also name as C20orf116, is a member of the DDRGK domain-containing protein family with unknown function. Depletion of DDRGK1 inhibits cell proliferation and invasion. Expression of NF-κB target genes showed the most significant decrease after depleting of DDRGK1, suggesting that DDRGK1 may play an important role in the NF-κB signaling pathway. DDRGK1 interacts with IκBα and regulates its stability, thereby regulates the NF-κB transcriptional activity. DDRGK1 acts as an important regulator of the NF-κB pathway. (PMID: 23675531) Catalog#21445-1-AP is a rabbit polyclonal antibody raised against the full-length of human DDRGK1.

 

 

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