TIMP2 Polyclonal antibody proteintech 17353-1-AP
$449.00
In stock
SKU
17353-1-AP
TIMP-2, CSC 21K, CSC-21K, Metalloproteinase inhibitor 2, TIMP 2
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse, Rat And More (1) | Immunogen: CatNo: Ag10051 Product name: Recombinant human TIMP2 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 6-220 aa of BC052605 Sequence: RTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP Predict reactive species |
| Applications: IHC, IF, ELISA | Observed Molecular Weight: 220 aa, 24 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: TIMP2 |
| Conjugate: Unconjugated | Gene Symbol: 7077 |
| Tested Applications: Positive IHC detected in | Gene ID (NCBI): AB_2287495 |
| Application: Immunohistochemistry (IHC) | RRID: Unconjugated |
| Dilution: IHC : 1:50-1:500 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Antigen affinity purification |
| Host / Isotype: Rabbit / IgG | Background Information: The TIMPs are natural highly specific endogenous inhibitors of MMPs. Human TIMP family consists of four 21-28 kDa proteins known as TIMP1, TIMP2, TIMP3, and TIMP4 encoded by four paralogous genes.TIMPs are vital to the maintenance of ECM homeostasis primarily through their MMP inhibitory functions. TIMP2, a member of the TIMP family, regulates the proteolytic activity of all MMPs and is involved in cell differentiation, growth, migration, angiogenesis, and apoptosis. Urinary TIMP2 has been recently recognized as an early biomarker to predict Acute kidney injury (AKI) in critically ill patients. |
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