GBP5 Polyclonal antibody proteintech 13220-1-AP
$449.00
In stock
SKU
13220-1-AP
EC:3.6.5.-, GBP-5, GBP-TA antigen, GTP-binding protein 5, Guanine nucleotide-binding protein 5
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: human, rat | Immunogen: CatNo: Ag4103 Product name: Recombinant human GBP5 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 382-586 aa of BC031639 Sequence: LETLLDAKQNDICKRNLEASSDYCSALLKDIFGPLEEAVKQGIYSKPGGHNLFIQKTEELKAKYYREPRKGIQAEEVLQKYLKSKESVSHAILQTDQALTETEKKKKEAQVKAEAEKAEAQRLAAIQRQNEQMMQERERLHQEQVRQMEIAKQNWLAEQQKMQEQQMQEQAAQLSTTFQAQNRSLLSELQHAQRTVNNDDPCVLL Predict reactive species |
| Applications: WB, IHC, IP, ELISA | Observed Molecular Weight: 586 aa, 67 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC031639 |
| Conjugate: Unconjugated | Gene Symbol: GBP5 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 115362 |
| Application: Western Blot (WB) | RRID: AB_2109348 |
| Dilution: WB : 1:2000-1:16000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: Guanylate binding protein (GBP) 5 belongs to the GBP family, which is involved in important cellular processes, including signal transduction, translation, vesicle trafficking, and exocytosis. GBP5 was reported to be a critical cellular factor in inflammasome assembly. Furthermore, GBP5 has been reported to induce inflammatory cytokines, including IL-1 beta and IL-18, through the activation of NLRP3 and AIM2. GBP5 encodes two isoforms: GBP-5a/b (67 kDa) and GBP-5ta (55 kDa) |