TRIM24 Polyclonal antibody proteintech 14208-1-AP

$449.00
In stock
SKU
14208-1-AP

 

TIF1-alpha, TIF1A, TIF1, RING-type E3 ubiquitin transferase TIF1-alpha, EC:2.3.2.27

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: human, mouse, rat Immunogen: CatNo: Ag5417 Product name: Recombinant human TRIM24 protein Source: e coli.-derived, T-HIS Tag: 6*His Domain: 701-1050 aa of BC028689 Sequence: SKPAGADSTHKVPVVMLEPIRIKQENSGPPENYDFPVVIVKQESDEESRPQNANYPRSILTSLLLNSSQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLHVGETRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYPEKRFPKPEFRNESEDNKFSDDSDDDFVQPRKKRLKSIEERQLLK Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, CoIP, ChIP, RIP, ELISA Observed Molecular Weight: 117 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC028689
Conjugate: Unconjugated Gene Symbol: TRIM24
Tested Applications: Positive WB detected in Gene ID (NCBI): 8805
Application: Western Blot (WB) RRID: AB_2256646
Dilution: WB : 1:2000-1:12000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: TRIM24, also named as RNF82, TIF1 and TIF1A, interacts selectively in vitro with the AF2-activating domain of the estrogen receptors. Association with DNA-bound estrogen receptors, it requires the presence of estradiol. It is a regulation protein of P53. Defects in TRIM24 are a cause of thyroid papillary carcinoma (TPC) wich is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue.

 

 

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